Anti-Debug & Anti-RE Techniques?

I'm interested in anti-debug and anti-reverse engineering methods, and can't seem to find any good examples that I can use. UPX is stupid since you can de-UPX anything packed with it, but Ollydbg is a very good tool in Debugging. Any good methods of anti-debugging?
A good place to start would be
You must know how people reverse programs to understand how you should protect your software.

are some channels that show you how reverse engineering is done.

There are some 'crackmes' + solutions available here:
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