Significance of assigning a number using bitwise operators


can anyone let me know the difference between at performance level, if any, between the following cases, during assignment?

case 1: #define Value_16 16


case 2: #define Value_16 (1<<4)

Thanks in advance.
There is no difference. These are both compile time constants.
Only a few nano seconds faster during _compiling_ using case #1 vs. case #2. The resultant executable code would be the same.

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