I need HELP with C++ and Arduino

I have to create a program where I need to send numbers from a text file to an Arduino UNO through a C++ program. But once I've managed to open the .txt files and gathered the data I don't know how to send it to the Arduino. Can someone help?? the data must be transferred by the program, I can't copy and paste it manually. Thanks
Which OS/Compiler are you running on the host machine.
The one with the file, and presumably the one with the need to write it in C++.

What is the connection between the two devices?
Serial, USB, Network, Bluetooth?
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